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A Phase 1, Open-Label, Dose Escalation and Expansion Study of TH1902 in Patients With Advanced Solid Tumors

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Trial Profile

A Phase 1, Open-Label, Dose Escalation and Expansion Study of TH1902 in Patients With Advanced Solid Tumors

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 03 Mar 2025

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At a glance

  • Drugs Sudocetaxel Zendusortide (Primary)
  • Indications Advanced breast cancer; Carcinoma; Cervical cancer; Colorectal cancer; Endometrial cancer; Fallopian tube cancer; Gynaecological cancer; HER2 positive breast cancer; Male breast cancer; Malignant melanoma; Non-small cell lung cancer; Ovarian cancer; Pancreatic cancer; Peritoneal cancer; Prostate cancer; Small cell lung cancer; Solid tumours; Thyroid cancer; Triple negative breast cancer
  • Focus Adverse reactions; First in man
  • Sponsors Theratechnologies
  • Most Recent Events

    • 26 Feb 2025 the company received FDA approval to proceed with an amendment to its Phase 1 study protocol to increase the dose of sudocetaxel zendusortide on the same weekly infusion cycle to 3.33 followed by 3.90 mg/kg/wk
    • 26 Feb 2025 According to Theratechnologies media release, the company received FDA approval to proceed with an amendment to its Phase 1 study protocol to increase the dose of sudocetaxel zendusortide on the same weekly infusion cycle to 3.33 followed by 3.90 mg/kg/wk,On January 31, 2025.
    • 09 Dec 2024 Results from Part 3 (dose optimization, weekly dosing schedule) of its ongoing Phase 1b trial of sudocetaxel zendusortide (TH1902) in patients with advanced ovarian cancer were presented in a Theratechnologies Media Release.

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