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A Randomized, Double-Blind, Placebo-Controlled Phase 1b/2a Study of NVG-291 in Spinal Cord Injury Subjects (CONNECT)

Trial Profile

A Randomized, Double-Blind, Placebo-Controlled Phase 1b/2a Study of NVG-291 in Spinal Cord Injury Subjects (CONNECT)

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 11 Jun 2025

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At a glance

  • Drugs NVG 291 (Primary)
  • Indications Spinal cord injuries
  • Focus Proof of concept; Therapeutic Use
  • Acronyms CONNECT
  • Sponsors NervGen Pharma

Most Recent Events

  • 02 Jun 2025 According to a NervGen Pharma media release, the company plans to meet with the FDA in the coming months to discuss these results and the path forward for NVG-291. In addition, we continue to enroll participants in the subacute cohort (20-90 days post injury) of the trial.
  • 02 Jun 2025 Primary(Connectivity in a leg muscle (tibialis anterior) end point was not met, according to a NervGen Pharma media release.
  • 02 Jun 2025 Primary (MEP amplitudes (corticospinal contribution) in two specific target muscle groups) endpoint has been met, According to a NervGen Pharma media release.

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