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Enhanced Melanoma Vaccine Against Neoantigen and Shared Antigens by CD40 Activation and TLR Agonists in Patients With Melanoma

Trial Profile

Enhanced Melanoma Vaccine Against Neoantigen and Shared Antigens by CD40 Activation and TLR Agonists in Patients With Melanoma

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 07 Mar 2026

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At a glance

  • Drugs CDX 1140 (Primary) ; CDX 1140 (Primary) ; Melanoma vaccine (Primary) ; Melanoma vaccine (Primary) ; Peptide vaccines (Primary) ; Peptide vaccines (Primary) ; Poly ICLC (Primary)
  • Indications Malignant melanoma; Skin cancer; Uveal melanoma
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms Mel66

Most Recent Events

  • 16 Jul 2024 Status changed from active, no longer recruiting to completed.
  • 10 Oct 2023 Status changed from recruiting to active, no longer recruiting.
  • 28 Sep 2020 Planned End Date changed from 1 Nov 2024 to 1 May 2025.

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