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A Phase 2a Multiple Ascending, Placebo-Controlled Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GFB-887, a TRPC5 Channel Inhibitor, in Patients With Diabetic Nephropathy, Focal Segmental Glomerulosclerosis, and Treatment-Resistant Minimal Change Disease

Trial Profile

A Phase 2a Multiple Ascending, Placebo-Controlled Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GFB-887, a TRPC5 Channel Inhibitor, in Patients With Diabetic Nephropathy, Focal Segmental Glomerulosclerosis, and Treatment-Resistant Minimal Change Disease

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 16 Nov 2022

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At a glance

  • Drugs GFB 887 (Primary)
  • Indications Diabetic nephropathies; Focal segmental glomerulosclerosis; Lipoid nephrosis
  • Focus Therapeutic Use
  • Acronyms TRACTION-2
  • Sponsors Goldfinch Bio

Most Recent Events

  • 10 Nov 2022 Status changed from recruiting to discontinued.
  • 22 Mar 2022 According to a Goldfinch Bio media release, the company will host a virtual event to discuss the recently announced preliminary clinical data from TRACTION-2 by Anthony Johnson, M.D, on March 29, 2022 at 4:00 p.m. ET; A live webcast of the event will be available under Videos & Features on the companys website at www.goldfinchbio.com. A replay of the webcast will be available on the Goldfinch Bio website following the event.
  • 28 Feb 2022 according to a Goldfinch Bio media release, results of prespecified interim analysis are expected in mid 2022.

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