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Phase II Study Evaluating HPV-16 Vaccination (ISA101b) and Pembrolizumab Plus Cisplatin Chemoradiotherapy for "Intermediate Risk" HPV-16 Associated Head and Neck Squamous Cell Carcinoma (HNSCC)

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Trial Profile

Phase II Study Evaluating HPV-16 Vaccination (ISA101b) and Pembrolizumab Plus Cisplatin Chemoradiotherapy for "Intermediate Risk" HPV-16 Associated Head and Neck Squamous Cell Carcinoma (HNSCC)

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 08 Oct 2024

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At a glance

  • Drugs Cisplatin (Primary) ; Peltopepimut-S (Primary) ; Pembrolizumab (Primary)
  • Indications Head and neck cancer; Oropharyngeal cancer; Squamous cell cancer
  • Focus Therapeutic Use

Most Recent Events

  • 04 Oct 2024 Planned number of patients changed from 50 to 18.
  • 04 Oct 2024 Planned End Date changed from 30 Jun 2027 to 20 Jun 2026.
  • 04 Oct 2024 Planned primary completion date changed from 30 Jun 2027 to 20 Jun 2025.

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