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To investigate the effect of CYP3A4 inhibition on evobrutinib PK and assessed the tolerability of the drug combinations in healthy subjects

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Trial Profile

To investigate the effect of CYP3A4 inhibition on evobrutinib PK and assessed the tolerability of the drug combinations in healthy subjects

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 06 May 2020

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At a glance

  • Drugs Evobrutinib (Primary) ; Fluconazole; Itraconazole
  • Indications Autoimmune disorders; Encephalomyelitis; Multiple sclerosis; Rheumatoid arthritis; Systemic lupus erythematosus
  • Focus Adverse reactions; Pharmacokinetics

Most Recent Events

  • 06 May 2020 New trial record
  • 21 Mar 2020 Results presented at the 121st Annual Meeting of the American Society for Clinical Pharmacology and Therapeutics

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