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A Phase 3 Randomized, Open-label Study to Evaluate the Efficacy and Safety of Olaparib Alone or in Combination With Bevacizumab Compared to Bevacizumab With a Fluoropyrimidine in Participants With Unresectable or Metastatic Colorectal Cancer Who Have Not Progressed Following First-line Induction (LYNK-003)

Trial Profile

A Phase 3 Randomized, Open-label Study to Evaluate the Efficacy and Safety of Olaparib Alone or in Combination With Bevacizumab Compared to Bevacizumab With a Fluoropyrimidine in Participants With Unresectable or Metastatic Colorectal Cancer Who Have Not Progressed Following First-line Induction (LYNK-003)

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 01 Nov 2024

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At a glance

  • Drugs Bevacizumab (Primary) ; Olaparib (Primary) ; Fluorouracil
  • Indications Adenocarcinoma; Colorectal cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms LYNK-003
  • Sponsors Merck Sharp & Dohme Corp.
  • Most Recent Events

    • 17 Oct 2023 Status changed from active, no longer recruiting to completed.
    • 04 Jul 2023 This trial has been completed in France, according to the European Clinical Trials Database record.
    • 10 May 2023 This trial has been completed in Hungary, according to European Clinical Trials Database record.

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