A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Assess the Efficacy and Safety of Ruxolitinib in Participants With COVID-19-Associated ARDS Who Require Mechanical Ventilation (RUXCOVID-DEVENT)
Latest Information Update: 05 Dec 2022
At a glance
- Drugs Ruxolitinib (Primary) ; Ruxolitinib (Primary)
- Indications SARS-CoV-2 acute respiratory disease
- Focus Registrational; Therapeutic Use
- Acronyms 369-DEVENT; RUXCOVID-DEVENT
- Sponsors Incyte Corporation
- 01 Dec 2022 Results assessing the safety and efficacy of the Janus kinase (JAK)1/JAK2 inhibitor ruxolitinib in COVID-19-associated acute respiratory distress syndrome requiring mechanical ventilation published in the Critical Care Medicine
- 18 Mar 2021 According to an Incyte Corporation media release, the company will discuss the results of the DEVENT study with regulatory authorities in the United States.
- 18 Mar 2021 Primary endpoint has not been met. (Proportion of participants who have died due to any cause), according to an Incyte Corporation media release.