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A Phase 1 Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AG-946 in Healthy Volunteers and in Subjects With Sickle Cell Disease

Trial Profile

A Phase 1 Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AG-946 in Healthy Volunteers and in Subjects With Sickle Cell Disease

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 17 Feb 2025

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At a glance

  • Drugs Tebapivat (Primary)
  • Indications Sickle cell anaemia
  • Focus Adverse reactions; First in man
  • Sponsors Agios Pharmaceuticals

Most Recent Events

  • 05 Nov 2024 According to an Agios Pharmaceuticals media release,data of this trial will be featured in oral and poster presentations during the 66th American Society of Hematology (ASH) Annual Meeting and Exposition in San Diego, California from December 7-10, 2024
  • 19 Jan 2024 Status changed from active, no longer recruiting to completed.
  • 13 Nov 2023 Status changed from recruiting to active, no longer recruiting.

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