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A Phase 2, Open Label, Randomized Study of the Efficacy and Safety of Acalabrutinib With Best Supportive Care Versus Best Supportive Care in Subjects Hospitalized With COVID-19

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Trial Profile

A Phase 2, Open Label, Randomized Study of the Efficacy and Safety of Acalabrutinib With Best Supportive Care Versus Best Supportive Care in Subjects Hospitalized With COVID-19

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 04 Nov 2021

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At a glance

  • Drugs Acalabrutinib (Primary)
  • Indications COVID-19 pneumonia; Respiratory insufficiency
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms CALAVI US
  • Sponsors AstraZeneca

    • Most Recent Events

    • 01 Dec 2020 Status changed from active, no longer recruiting to completed.
    • 12 Nov 2020 Primary endpoint of Proportion of subjects alive and free of respiratory failure has not been met, According to an AstraZeneca media release
    • 17 Sep 2020 Planned End Date changed from 30 Nov 2020 to 19 Nov 2020.

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