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A Phase 2/3, Randomized, Double Blind, Placebo-controlled Study to Evaluate the Efficacy and the Safety of ABX464 in Treating Inflammation and Preventing COVID-19 Associated Acute Respiratory Failure in Patients Aged ≥ 65 and Patients Aged ≥18 With at Least One Additional Risk Factor Who Are Infected With SARS-CoV-2

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Trial Profile

A Phase 2/3, Randomized, Double Blind, Placebo-controlled Study to Evaluate the Efficacy and the Safety of ABX464 in Treating Inflammation and Preventing COVID-19 Associated Acute Respiratory Failure in Patients Aged ≥ 65 and Patients Aged ≥18 With at Least One Additional Risk Factor Who Are Infected With SARS-CoV-2

Status: Discontinued
Phase of Trial: Phase II/III

Latest Information Update: 06 Oct 2021

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At a glance

  • Drugs Obefazimod (Primary)
  • Indications Adult respiratory distress syndrome; Inflammation; Respiratory insufficiency; SARS-CoV-2 acute respiratory disease
  • Focus Registrational; Therapeutic Use
  • Acronyms Mir-Age
  • Sponsors Abivax

Most Recent Events

  • 01 May 2021 This trial has been completed in Germany, according to European Clinical Trials Database record.
  • 11 Mar 2021 This trial has been Discontinued in France, according to European Clinical Trials Database record.
  • 05 Mar 2021 According to an Abivax media release, the company announces that it is halting the miR-AGE phase 2b/3 clinical trial in high-risk Covid-19 patients after the independent Data Safety and Monitoring Board (DSMB) recommendation for lack of efficacy

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