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A Phase 0/2 Study of LY3214996 (ERK Inhibitor) in Combination with Abemaciclib (CDK4 and 6 Inhibitor) in Recurrent Glioblastoma Participants Scheduled for Resection to Evaluate Central Nervous System (CNS) Penetration

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Trial Profile

A Phase 0/2 Study of LY3214996 (ERK Inhibitor) in Combination with Abemaciclib (CDK4 and 6 Inhibitor) in Recurrent Glioblastoma Participants Scheduled for Resection to Evaluate Central Nervous System (CNS) Penetration

Status: Active, no longer recruiting
Phase of Trial: Phase 0

Latest Information Update: 05 Mar 2025

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At a glance

  • Drugs Abemaciclib (Primary) ; Temuterkib (Primary)
  • Indications Glioblastoma; Glioma
  • Focus Pharmacokinetics; Therapeutic Use

Most Recent Events

  • 28 Feb 2025 Planned End Date changed from 1 Feb 2025 to 13 Feb 2028.
  • 28 Feb 2025 Status changed from recruiting to active, no longer recruiting.
  • 25 Mar 2024 Planned End Date changed from 1 Feb 2024 to 1 Feb 2025.

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