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Assessment of Brain O-GlcNAcase (OGA) Enzyme Occupancy After Multiple Oral Doses of LY3372689 as Measured by Positron Emission Tomography (PET) With the Radioligand [18F]LY3316612 in Healthy Subjects

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Trial Profile

Assessment of Brain O-GlcNAcase (OGA) Enzyme Occupancy After Multiple Oral Doses of LY3372689 as Measured by Positron Emission Tomography (PET) With the Radioligand [18F]LY3316612 in Healthy Subjects

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 04 Nov 2021

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At a glance

  • Drugs LY 3372689 (Primary)
  • Indications Alzheimer's disease
  • Focus Pharmacodynamics
  • Sponsors Eli Lilly and Company
  • Most Recent Events

    • 30 Jul 2021 Results from NCT03944031 and NCT04392271 assessing effect of LY3372689 on brain OGA enzyme occupancy, presented at the Alzheimer's Association International Conference 2021
    • 03 Nov 2020 Status changed from recruiting to completed.
    • 16 Oct 2020 Planned End Date changed from 12 Oct 2020 to 14 Dec 2020.

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