A Randomized, Double-blind, Placebo-Controlled, Active-Comparator, Multicenter, Phase 3 Study of Brentuximab Vedotin or Placebo in Combination With Lenalidomide and Rituximab in Subjects With Relapsed or Refractory Diffuse Large B-cell Lymphoma (DLBCL)

Status: Active, no longer recruiting

Phase of Trial: Phase III

Latest Information Update: 22 Apr 2025

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At a glance

Drugs Brentuximab vedotin (Primary) ; Lenalidomide; Rituximab; Rituximab
Indications Diffuse large B cell lymphoma
Focus Registrational; Therapeutic Use
Acronyms ECHELON-3
Sponsors Seagen

Most Recent Events

17 Apr 2025 Planned End Date changed from 30 Apr 2027 to 30 Nov 2025.
17 Apr 2025 Planned primary completion date changed from 31 May 2025 to 30 Nov 2025.
12 Feb 2025 According to a Pfizer media release, Detailed data from ECHELON-3 were published in JCO Oncology Practice on January 7, 2025 and presented at the 2024 American Society of Clinical Oncology (ASCO) Annual Meeting.

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