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A Phase II Two Cohorts Prospective Study to Evaluate the Efficacy and Safety of Tislelizumab Combined With Chemotherapy With or Without Bevacizumab in Non-squamous NSCLC With EGFR Sensitizing Mutation Who Failed EGFR TKI Therapy

Trial Profile

A Phase II Two Cohorts Prospective Study to Evaluate the Efficacy and Safety of Tislelizumab Combined With Chemotherapy With or Without Bevacizumab in Non-squamous NSCLC With EGFR Sensitizing Mutation Who Failed EGFR TKI Therapy

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 10 Dec 2021

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At a glance

  • Drugs Bevacizumab (Primary) ; Carboplatin (Primary) ; Paclitaxel (Primary) ; Pemetrexed (Primary) ; Tislelizumab (Primary)
  • Indications Non-small cell lung cancer
  • Focus Therapeutic Use

Most Recent Events

  • 02 Dec 2021 According to a BeiGene media release, results from the study will be presented at the European Society for Medical Oncology Immuno-Oncology (ESMO IO) Congress 2021.
  • 19 Nov 2021 Number of treatment arms have been increased from 1 to 2 by the addition of Tislelizumab plus chemotherapy plus Bevacizumab arm. Study design has been changed from single group assignment to parallel.
  • 19 Nov 2021 Planned number of patients changed from 66 to 120.

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