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I-SPY COVID TRIAL: An Adaptive Platform Trial to Reduce Mortality and Ventilator Requirements for Critically Ill Patients

Trial Profile

I-SPY COVID TRIAL: An Adaptive Platform Trial to Reduce Mortality and Ventilator Requirements for Critically Ill Patients

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 21 Mar 2024

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At a glance

  • Drugs Apremilast (Primary) ; Aviptadil (Primary) ; Celecoxib (Primary) ; Cenicriviroc (Primary) ; Dornase alfa (Primary) ; Famotidine (Primary) ; Icatibant (Primary) ; Narsoplimab (Primary) ; Razuprotafib (Primary) ; Remdesivir (Primary)
  • Indications Adult respiratory distress syndrome; COVID 2019 infections; COVID-19 respiratory infection
  • Focus Therapeutic Use
  • Acronyms I-SPY COVID; I-SPY COVID
  • Most Recent Events

    • 12 Mar 2024 Planned End Date changed from 1 Nov 2024 to 31 Jul 2030.
    • 12 Mar 2024 Planned primary completion date changed from 24 Jul 2023 to 31 Jul 2028.
    • 05 Feb 2024 Planned End Date changed from 1 Nov 2023 to 1 Nov 2024.
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