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Phase II Maintenance Trial of Nivolumab for Newly Diagnosed PCNSL Patients With Persistent Circulating Tumor DNA in the CSF After Completion of Methotrexate-Based First-Line Induction Chemotherapy

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Trial Profile

Phase II Maintenance Trial of Nivolumab for Newly Diagnosed PCNSL Patients With Persistent Circulating Tumor DNA in the CSF After Completion of Methotrexate-Based First-Line Induction Chemotherapy

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 30 Jan 2026

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At a glance

  • Drugs Nivolumab (Primary)
  • Indications CNS cancer; Lymphoma
  • Focus Adverse reactions; Therapeutic Use

Most Recent Events

  • 27 Jan 2026 Status changed from active, no longer recruiting to completed.
  • 29 Nov 2023 Status changed from recruiting to active, no longer recruiting.
  • 22 Aug 2023 Planned End Date changed from 22 May 2023 to 22 May 2026.

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