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EMPACT-MI: A Streamlined, Multicentre, Randomised, Parallel Group, Double-blind Placebo-controlled Superiority Trial to Evaluate the Effect of EMPAgliflozin on Hospitalisation for Heart Failure and Mortality in Patients With aCuTe Myocardial Infarction

Trial Profile

EMPACT-MI: A Streamlined, Multicentre, Randomised, Parallel Group, Double-blind Placebo-controlled Superiority Trial to Evaluate the Effect of EMPAgliflozin on Hospitalisation for Heart Failure and Mortality in Patients With aCuTe Myocardial Infarction

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 02 May 2025

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At a glance

  • Drugs Empagliflozin (Primary)
  • Indications Heart failure
  • Focus Registrational; Therapeutic Use
  • Acronyms EMPACT-MI
  • Sponsors Boehringer Ingelheim; Boehringer Ingelheim GmbH International

Most Recent Events

  • 11 Apr 2025 Results evaluating empagliflozin treatment in acute myocardial infarction published in the International Journal of Cardiology.
  • 30 Apr 2024 Results published in the Eli lilly media Release showed a 10% relative risk reduction in time to first hospitalization due to heart failure or all-cause mortality for Jardiance versus placebo, which did not reach statistical significance.
  • 06 Apr 2024 According to Eli lilly media release, results presented at the American College of Cardiologys 2024 Scientific Session & Expo

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