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An open label study to investigate the ruxolitinib–fluconazole drug interaction by determining the effect of multiple doses of fluconazole on the PK of ruxolitinib administered as a single dose in healthy subjects

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An open label study to investigate the ruxolitinib–fluconazole drug interaction by determining the effect of multiple doses of fluconazole on the PK of ruxolitinib administered as a single dose in healthy subjects

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 03 Jun 2020

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At a glance

  • Drugs Fluconazole (Primary) ; Ruxolitinib (Primary)
  • Indications Acute myeloid leukaemia; Adult respiratory distress syndrome; Alopecia areata; Atopic dermatitis; Breast cancer; Breast disorders; Bronchiolitis obliterans; Cachexia; Chronic lymphocytic leukaemia; Chronic myeloid leukaemia; Chronic myelomonocytic leukaemia; Essential thrombocythaemia; Graft-versus-host disease; Haematological malignancies; Head and neck cancer; Hodgkin's disease; Multiple myeloma; Myelodysplastic syndromes; Myelofibrosis; Pneumonia; Polycythaemia vera; Precursor cell lymphoblastic leukaemia-lymphoma; Thalassaemia; Vitiligo
  • Focus Pharmacokinetics
  • Sponsors Novartis Pharma A.G.

    • Most Recent Events

    • 03 Jun 2020 New trial record

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