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A Phase 2 Randomized Study of Osimertinib Versus Osimertinib Plus Chemotherapy for Patients With Metastatic EGFR-Mutant Lung Cancers That Have Detectable EGFR-Mutant cfDNA in Plasma After Initiation of Osimertinib

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Trial Profile

A Phase 2 Randomized Study of Osimertinib Versus Osimertinib Plus Chemotherapy for Patients With Metastatic EGFR-Mutant Lung Cancers That Have Detectable EGFR-Mutant cfDNA in Plasma After Initiation of Osimertinib

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 13 Jun 2025

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At a glance

  • Drugs Carboplatin (Primary) ; Osimertinib (Primary) ; Pemetrexed (Primary)
  • Indications Non-small cell lung cancer
  • Focus Therapeutic Use

Most Recent Events

  • 08 Jun 2025 Planned End Date changed from 1 May 2025 to 1 May 2026.
  • 08 Jun 2025 Planned primary completion date changed from 1 May 2025 to 1 May 2026.
  • 20 Mar 2024 Planned End Date changed from 1 May 2024 to 1 May 2025.

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