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A Phase 1/2 Study of REGN7257 (Anti-Interleukin 2 Receptor Subunit Gamma [IL2RG] Monoclonal Antibody) in Patients With Severe Aplastic Anemia That Is Refractory to or Relapsed on Immunosuppressive Therapy

Trial Profile

A Phase 1/2 Study of REGN7257 (Anti-Interleukin 2 Receptor Subunit Gamma [IL2RG] Monoclonal Antibody) in Patients With Severe Aplastic Anemia That Is Refractory to or Relapsed on Immunosuppressive Therapy

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 17 Feb 2026

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At a glance

  • Drugs REGN 7257 (Primary)
  • Indications Aplastic anaemia
  • Focus Adverse reactions; First in man; Therapeutic Use
  • Sponsors Regeneron Pharmaceuticals

Most Recent Events

  • 13 Nov 2025 According to Regeneron Pharmaceuticals media release, data from the trial will be presented at the American Society of Hematology (ASH) 2025 Annual Meeting, taking place from December 6-9 in Orlando, FL.
  • 09 Jul 2025 Status changed from suspended to discontinued.
  • 20 Dec 2024 Planned End Date changed from 10 May 2026 to 13 Jul 2026.

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