Trial Profile

Phase I Study of CRISPR-Cas9 Mediated PD-1 Gene-knocked Out Mesothelin-directed CAR-T Cells With the Conditioning Regimen of Paclitaxel and Cyclophosphamide in Mesothelin Positive Multiple Solid Tumors

Status: Active, no longer recruiting

Phase of Trial: Phase I

Latest Information Update: 04 Nov 2021

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At a glance

Drugs GC 008T (Primary) ; Cyclophosphamide; Paclitaxel
Indications Cholangiocarcinoma; Colorectal cancer; Ovarian cancer; Pancreatic cancer; Solid tumours
Focus Adverse reactions

05 Jun 2020 New trial record
31 May 2020 Status changed from recruiting to active, no longer recruiting as per results presented at the 56th Annual Meeting of the American Society of Clinical Oncology
31 May 2020 Results presented at the 56th Annual Meeting of the American Society of Clinical Oncology

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