Trial Profile

A Randomized, Open-label, Multi-arm, Two-part, Phase II Study to Assess Efficacy and Safety of Multiple LXH254 Combinations in Patients With Previously Treated Unresectable or Metastatic BRAFV600 or NRAS Mutant Melanoma

Status: Active, no longer recruiting

Phase of Trial: Phase II

Latest Information Update: 11 Apr 2025

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At a glance

Drugs Naporafenib (Primary) ; Ribociclib (Primary) ; Rineterkib (Primary) ; Trametinib (Primary)
Indications Malignant melanoma; Skin cancer
Focus Therapeutic Use
Sponsors Novartis; Novartis Pharmaceuticals

04 Apr 2025 Planned End Date changed from 27 Mar 2025 to 30 Jul 2025.
04 Apr 2025 Planned primary completion date changed from 26 Feb 2025 to 30 Jun 2025.
20 Dec 2024 Planned End Date changed from 27 Dec 2024 to 27 Mar 2025.

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