Trial Profile

A Phase Ib/II Study of Pembrolizumab, Ibrutinib and Rituximab in Refractory/Relapsed Primary Central Nervous System Lymphoma (PCNSL)

Status: Recruiting

Phase of Trial: Phase I/II

Latest Information Update: 25 Feb 2026

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At a glance

Drugs Ibrutinib (Primary) ; Pembrolizumab (Primary) ; Rituximab (Primary)
Indications CNS cancer; Lymphoma
Focus Therapeutic Use

Most Recent Events

20 Feb 2026 Planned End Date changed from 5 Jan 2026 to 5 Jan 2027.
20 Feb 2026 Planned primary completion date changed from 5 Dec 2025 to 5 Dec 2026.
05 Mar 2025 Planned End Date changed from 5 Mar 2025 to 5 Jan 2026.

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