Trial Profile

Randomized, Double-Blind, Placebo-Controlled Phase 2 Study of the Efficacy and Safety of Intravenous Pamrevlumab, a Monoclonal Antibody Against Connective Tissue Growth Factor (CTGF), in Hospitalized Patients With Acute COVID-19 Disease

Status: Discontinued

Phase of Trial: Phase II

Latest Information Update: 06 Feb 2026

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At a glance

Drugs Pamrevlumab (Primary)
Indications COVID 2019 infections; COVID-19 pneumonia; SARS-CoV-2 acute respiratory disease
Focus Proof of concept; Therapeutic Use
Sponsors Kyntra Bio

07 Jan 2026 According to FibroGen media release, FibroGen is now called as Kyntra Bio.
31 Mar 2021 Status changed from recruiting to discontinued.(The study was terminated by Sponsor due to low enrollment).
23 Jun 2020 According to a FibroGen media release, first patient has been enrolled in to the trial.

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