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A Randomized, Double-Blind, Adaptive, Phase II/III Study of GSK3359609 in Combination With Pembrolizumab and 5FU-Platinum Chemotherapy Versus Placebo in Combination With Pembrolizumab Plus 5FU-Platinum Chemotherapy for First-Line Treatment of Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma

Trial Profile

A Randomized, Double-Blind, Adaptive, Phase II/III Study of GSK3359609 in Combination With Pembrolizumab and 5FU-Platinum Chemotherapy Versus Placebo in Combination With Pembrolizumab Plus 5FU-Platinum Chemotherapy for First-Line Treatment of Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma

Status: Discontinued
Phase of Trial: Phase II/III

Latest Information Update: 14 Oct 2024

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At a glance

  • Drugs Feladilimab (Primary) ; Pembrolizumab (Primary) ; Carboplatin; Cisplatin; Fluorouracil
  • Indications Carcinoma; Head and neck cancer; Squamous cell cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms INDUCE-4
  • Sponsors GlaxoSmithKline; GlaxoSmithKline Research & Development; GSK
  • Most Recent Events

    • 10 Mar 2024 This trial has been completed in Greece (End date: 2023-09-19), according to European Clinical Trials Database record.
    • 07 Dec 2023 This trial has been completed in Poland (End date: 2023-09-19), according to European Clinical Trials Database record.
    • 05 Nov 2023 This trial has been completed in Germnay, according to European Clinical Trials Database record

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