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Effects of GSK3640254 on the Single-Dose Pharmacokinetics of Probe Substrates (Caffeine, Metoprolol, Montelukast, Flurbiprofen, Omeprazole, Midazolam, Digoxin, and Pravastatin) in Healthy Subjects

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Trial Profile

Effects of GSK3640254 on the Single-Dose Pharmacokinetics of Probe Substrates (Caffeine, Metoprolol, Montelukast, Flurbiprofen, Omeprazole, Midazolam, Digoxin, and Pravastatin) in Healthy Subjects

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 01 Mar 2023

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At a glance

  • Drugs Fipravirimat (Primary) ; Caffeine; Digoxin; Flurbiprofen; Metoprolol; Midazolam; Montelukast; Omeprazole; Pravastatin
  • Indications HIV infections
  • Focus Pharmacokinetics
  • Sponsors ViiV Healthcare

Most Recent Events

  • 23 Feb 2023 Results assessing pharmacokinetics of GSK3640254 and a Metabolic Probe Cocktail in Healthy Participants published in the British Journal of Clinical Pharmacology
  • 13 Apr 2021 Status changed from recruiting to completed.
  • 17 Sep 2020 Planned End Date changed from 16 Oct 2020 to 15 Apr 2021.

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