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A First-in Human Trial to Study Safety and Tolerability of Single Rising Intravitreal dOses (Open Label, Non-randomized, Uncontrolled) and in Addition the Early Biological Response of Multiple intravitReal Dosing (Single-masked, raNdomized, Sham-controlled) of BI 764524 in panretinaL Photocoagulation (PRP) Treated proLiferative Diabetic Retinopathy (PDR) Patients With Diabetic Macular Ischemia (DMI) - the HORNBILL Study

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A First-in Human Trial to Study Safety and Tolerability of Single Rising Intravitreal dOses (Open Label, Non-randomized, Uncontrolled) and in Addition the Early Biological Response of Multiple intravitReal Dosing (Single-masked, raNdomized, Sham-controlled) of BI 764524 in panretinaL Photocoagulation (PRP) Treated proLiferative Diabetic Retinopathy (PDR) Patients With Diabetic Macular Ischemia (DMI) - the HORNBILL Study

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 24 May 2024

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At a glance

  • Drugs BI 764524 (Primary)
  • Indications Diabetic retinopathy
  • Focus Adverse reactions; First in man
  • Acronyms HORNBILL
  • Sponsors Boehringer Ingelheim

    • Most Recent Events

    • 06 May 2024 According to Boehringer Ingelheim Media Release data from the study were presented at the Association for Research in Vision and Ophthalmology (ARVO) Annual meeting 2024
    • 06 May 2024 Results presented in the Boehringer Ingelheim Media Release
    • 11 May 2023 Status changed from active, no longer recruiting to completed.

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