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Safety and Efficacy Study of Pembrolizumab in Combination With LENvatinib in Participants With Hepatocellular Carcinoma (HCC) Before Liver Transplant as Neoadjuvant TherapY——PLENTY Randomized Clinical Trial

Trial Profile

Safety and Efficacy Study of Pembrolizumab in Combination With LENvatinib in Participants With Hepatocellular Carcinoma (HCC) Before Liver Transplant as Neoadjuvant TherapY——PLENTY Randomized Clinical Trial

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 07 Aug 2023

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At a glance

  • Drugs Lenvatinib (Primary) ; Pembrolizumab (Primary)
  • Indications Cholangiocarcinoma; Liver cancer
  • Focus Therapeutic Use
  • Acronyms PLENTY202001

Most Recent Events

  • 24 Jun 2023 Results (n=22) assessing whether programmed death receptor 1 (PD-1) blockadeplus lenvatinib as a neoadjuvant therapy before LT allows safelyadministered and effectively reduces post-LT recurrence for those patients with hepatocellular carcinoma beyond Milan criteria presented at the European Association for the Study of the Liver Congress 2023
  • 12 Aug 2020 Status changed from active, no longer recruiting to recruiting.
  • 06 Aug 2020 Planned number of patients changed from 220 to 192.

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