Trial Profile

A First -in Human Phase I, Non-randomized, Open-label, Multi-center Dose Escalation Trial of BI 764532 Administered by Repeated Intravenous Infusions in Patients With Small Cell Lung Carcinoma and Other Neuroendocrine Neoplasms Expressing DLL3

Status: Recruiting

Phase of Trial: Phase I

Latest Information Update: 04 Jun 2025

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At a glance

Drugs Obrixtamig (Primary)
Indications Carcinoma; Large cell carcinoma; Lung cancer; Neuroendocrine carcinoma; Neuroendocrine tumours; Small cell lung cancer
Focus Adverse reactions; First in man
Sponsors Boehringer Ingelheim

22 May 2025 According to a Boehringer Ingelheim media release, company will present the latest data from this trial at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting.
06 Dec 2024 Planned End Date changed from 22 Sep 2025 to 15 Dec 2025.
25 Sep 2024 Planned primary completion date changed from 2 Sep 2024 to 22 Sep 2025.

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