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Phase2 trial of oxaliplatin, irinotecan and S-1 (OX-IRIS) as first line chemotherapy for unresectable pancreatic cancer (HGCSG1803)

Trial Profile

Phase2 trial of oxaliplatin, irinotecan and S-1 (OX-IRIS) as first line chemotherapy for unresectable pancreatic cancer (HGCSG1803)

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 25 Oct 2024

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At a glance

  • Drugs Gimeracil/oteracil/tegafur (Primary) ; Irinotecan (Primary) ; Oxaliplatin (Primary)
  • Indications Pancreatic cancer
  • Focus Therapeutic Use

Most Recent Events

  • 20 Jan 2024 Primary endpoint (objective response rate (ORR) has been met according to Results presented at the 2024 Gastrointestinal Cancers Symposium.
  • 20 Jan 2024 Results (n=39) assessing safety and efficacy of oxaliplatin, irinotecan and S-1 combination therapy (OX-IRIS) in metastatic pancreatic cancer as first line treatment presented at the 2024 Gastrointestinal Cancers Symposium
  • 01 Jul 2023 Results assessing To evaluate Efficacy and safety of OX-IRIS, HGCSG1803 study has conductedas a multicenter, non-randomized, single arm, prospective, phase II study in Japan presented at the 25th World Congress on Gastrointestinal Cancer

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