Trial Profile

P-RAD: A Randomized Study of Preoperative Chemotherapy, Pembrolizumab and No, Low or High Dose RADiation in Node-Positive, HER2-Negative Breast Cancer

Status: Active, no longer recruiting

Phase of Trial: Phase II

Latest Information Update: 20 Aug 2025

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At a glance

Drugs Capecitabine (Primary) ; Carboplatin (Primary) ; Cyclophosphamide (Primary) ; Doxorubicin (Primary) ; Paclitaxel (Primary) ; Pembrolizumab (Primary)
Indications Early breast cancer; HER2 negative breast cancer; Male breast cancer; Triple negative breast cancer
Focus Therapeutic Use
Acronyms P-RAD

Most Recent Events

06 Aug 2025 Planned End Date changed from 1 Dec 2024 to 1 Aug 2027.
06 Aug 2025 Planned primary completion date changed from 1 Jun 2024 to 1 Aug 2025.
06 Aug 2025 Status changed from recruiting to active, no longer recruiting.

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