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A Phase 2, Open Label, Randomized Study of the Efficacy and Safety of STI-5656 (Abivertinib Maleate) With Standard of Care Versus Standard of Care in Subjects Hospitalized With COVID-19

Trial Profile

A Phase 2, Open Label, Randomized Study of the Efficacy and Safety of STI-5656 (Abivertinib Maleate) With Standard of Care Versus Standard of Care in Subjects Hospitalized With COVID-19

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 20 Jan 2023

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At a glance

  • Drugs Abivertinib (Primary)
  • Indications COVID-19 pneumonia; Respiratory insufficiency; SARS-CoV-2 acute respiratory disease
  • Focus Therapeutic Use
  • Sponsors Sorrento Therapeutics
  • Most Recent Events

    • 27 Oct 2021 Status changed from active, no longer recruiting to completed, according to a Sorrento Therapeutics media release.
    • 27 Oct 2021 Preliminary results presented in a Sorrento Therapeutics media release.
    • 22 Jun 2021 According to a Sorrento Therapeutics media release, last patient randomized on 7 Apr 2021 in this trial with topline data expected in 3Q2021, If positive, the results of the two parallel and independently run clinical trials (NCT04440007 and NCT04528667) should provide valuable insights into the ability of Abivertinib to help patients with pulmonary distress associated with cytokine storm induced by COVID-19.

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