A Phase 1 Study to Evaluate the Safety, Tolerability, and Preliminary Efficacy of Denikitug (GS-1811), an Afucosylated Anti-CCR8 Monoclonal Antibody, as Monotherapy and in Combination With an Anti-PD-1 Monoclonal Antibody in Adults With Advanced Solid Tumors
Latest Information Update: 11 Sep 2025
At a glance
- Drugs Denikitug (Primary) ; Zimberelimab (Primary)
- Indications Solid tumours
- Focus Adverse reactions; First in man
- Sponsors Gilead Sciences
Most Recent Events
- 25 Jul 2025 Planned number of patients changed from 376 to 416.
- 25 Jul 2025 Planned End Date changed from 1 Dec 2027 to 1 Dec 2028.
- 25 Jul 2025 Planned primary completion date changed from 1 Dec 2027 to 1 Dec 2028.