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A Phase 3, Randomized, Open-Label, Controlled Study of Cabozantinib (XL184) in Combination With Atezolizumab vs Second Novel Hormonal Therapy (NHT) in Subjects With Metastatic Castration-Resistant Prostate Cancer

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Trial Profile

A Phase 3, Randomized, Open-Label, Controlled Study of Cabozantinib (XL184) in Combination With Atezolizumab vs Second Novel Hormonal Therapy (NHT) in Subjects With Metastatic Castration-Resistant Prostate Cancer

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 28 Nov 2024

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At a glance

  • Drugs Atezolizumab (Primary) ; Cabozantinib (Primary) ; Abiraterone acetate; Enzalutamide; Prednisone
  • Indications Adenocarcinoma; Pelvic cancer; Prostate cancer; Soft tissue sarcoma
  • Focus Registrational; Therapeutic Use
  • Acronyms CONTACT-02
  • Sponsors Exelixis

Most Recent Events

  • 15 Sep 2024 According to Ipsen Media Release, company announced detailed final overall survival (OS) data from the Phase III CONTACT-02 trial investigating the combination of Cabometyx (cabozantinib) and atezolizumab in metastatic castration-resistant prostate cancer (mCRPC).
  • 15 Sep 2024 Results Presented in the Ipsen Media Release.
  • 15 Sep 2024 According to an Exelixis media release, Exelixis intends to submit a supplemental New Drug Application with the U.S. Food and Drug Administration for cabozantinib in combination with atezolizumab for mCRPC later this year.

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