LOC-R01: Randomized Phase IB/II Study of Escalating Doses of Lenalidomide and Ibrutinib in Association With R-MPV as a Targeted Induction Treatment for Patients Aged 18 to 60 (up to 65 for Phase II) With a Newly Diagnosed Primary Central Nervous System Lymphoma

Status: Active, no longer recruiting

Phase of Trial: Phase I/II

Latest Information Update: 15 Apr 2025

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At a glance

Drugs Ibrutinib (Primary) ; Lenalidomide (Primary) ; Methotrexate; Prednisone; Procarbazine; Rituximab; Vincristine
Indications CNS cancer; Diffuse large B cell lymphoma; Lymphoma
Focus Adverse reactions; Therapeutic Use
Acronyms LOC-R01

Most Recent Events

10 Apr 2025 Planned End Date changed from 28 Feb 2035 to 30 Aug 2035.
10 Apr 2025 Planned primary completion date changed from 28 Feb 2025 to 30 Aug 2025.
10 Apr 2025 Status changed from recruiting to active, no longer recruiting.

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