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A Multi-Center, Open-Label, Phase 1/2 Clinical Trial to Evaluate the Safety and Anti-Tumor Activity of AB-101 Monotherapy and AB-101 With Immunotherapy in Patients With Relapsed/Refractory Non-Hodgkin Lymphoma of B-Cell Origin

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Trial Profile

A Multi-Center, Open-Label, Phase 1/2 Clinical Trial to Evaluate the Safety and Anti-Tumor Activity of AB-101 Monotherapy and AB-101 With Immunotherapy in Patients With Relapsed/Refractory Non-Hodgkin Lymphoma of B-Cell Origin

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 15 Feb 2024

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At a glance

  • Drugs AB 101 Artiva Biotherapeutics (Primary) ; Bendamustine (Primary) ; Cyclophosphamide (Primary) ; Fludarabine (Primary) ; Interleukin-2 (Primary) ; Rituximab (Primary)
  • Indications B-cell lymphoma; Diffuse large B cell lymphoma; Non-Hodgkin's lymphoma
  • Focus Adverse reactions; First in man; Therapeutic Use
  • Sponsors Artiva Biotherapeutics

    • Most Recent Events

    • 07 Aug 2023 Planned number of patients changed from 93 to 108.
    • 09 Jun 2023 According to an Artiva Biotherapeutics Media Release, data from this trial were presented at the 2023 ASCO Annual Meeting.
    • 06 Jun 2023 Results (n=17) assessing safety and efficacy of AB-101 evaluated as monotherapy or in combination with rituximab in R/R non-Hodgkin lymphoma presented at the 59th Annual Meeting of the American Society of Clinical Oncology

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