A Phase Ia/Ib Dose-Escalation and Dose-Expansion Study Evaluating the Safety, Pharmacokinetics, and Activity of GDC-6036 as a Single Agent and in Combination With Other Anti-cancer Therapies in Patients With Advanced or Metastatic Solid Tumors With a KRAS G12C Mutation
Latest Information Update: 19 Mar 2026
At a glance
- Drugs Atezolizumab (Primary) ; Bevacizumab (Primary) ; Cetuximab (Primary) ; Divarasib (Primary) ; Erlotinib (Primary) ; Inavolisib (Primary) ; Migoprotafib (Primary)
- Indications Adenocarcinoma; Advanced breast cancer; Anal cancer; Appendiceal cancer; Cholangiocarcinoma; Colorectal cancer; Duodenal neoplasms; Endometrial cancer; Gastric cancer; Lung cancer; Neuroendocrine tumours; Non-small cell lung cancer; Pancreatic cancer; Solid tumours
- Focus Adverse reactions
- Sponsors Genentech
Most Recent Events
- 12 Feb 2026 Planned End Date changed from 24 Sep 2025 to 31 Dec 2027.
- 12 Feb 2026 Planned primary completion date changed from 24 Sep 2025 to 31 Dec 2027.
- 16 Oct 2025 Planned End Date changed from 28 Feb 2026 to 24 Sep 2025.