Trial Profile

A Randomised, Single Blind, Placebo Controlled, Phase 1 Trial to Evaluate the Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Activity of Ruxolitinib When Co-administered With Artemether-lumefantrine in Healthy Participants

Status: Completed

Phase of Trial: Phase I

Latest Information Update: 01 Nov 2021

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At a glance

25 Oct 2021 Results assessing the safety, tolerability, pharmacokinetic and pharmacodynamic profile for the combination of ruxolitinib and the approved artemisinin based combination, artemether-lumefantrine, widely used for the treatment of uncomplicated malaria, published in the Antimicrobial Agents and Chemotherapy.
23 Nov 2020 Status changed from recruiting to completed.
22 Sep 2020 Planned End Date changed from 31 Mar 2021 to 31 Jan 2021.

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