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Treatment of Renal Failure Due to Myeloma Cast Nephropathy: Comparison of Two Different Chemotherapy Regimens and Evaluation of Optimized Removal of Monoclonal Immunoglobulin Light Chains Using a High Permeability Hemodialysis Membrane

Trial Profile

Treatment of Renal Failure Due to Myeloma Cast Nephropathy: Comparison of Two Different Chemotherapy Regimens and Evaluation of Optimized Removal of Monoclonal Immunoglobulin Light Chains Using a High Permeability Hemodialysis Membrane

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 08 Jul 2020

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At a glance

  • Drugs Bortezomib (Primary) ; Cyclophosphamide (Primary) ; Dexamethasone (Primary) ; Methylprednisolone
  • Indications Multiple myeloma
  • Focus Therapeutic Use
  • Acronyms MYRE

Most Recent Events

  • 08 Jul 2020 New trial record
  • 23 Jun 2020 Primary endpoint has not been met. (Prevalence of renal response (if dialysis not mandatory at baseline: strata 1); Prevalence of patients free of dialysis (if dialysis required at baseline; strata 2))
  • 23 Jun 2020 Results published in the Journal of Clinical Oncology

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