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A retrospective study to compare immunogenicity in chronic liver disease patients on treatment with two dose vaccine (Heplisav-B) and conventional three-dose vaccine (Engerix-B) and to identify factors that predict seroconversion

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A retrospective study to compare immunogenicity in chronic liver disease patients on treatment with two dose vaccine (Heplisav-B) and conventional three-dose vaccine (Engerix-B) and to identify factors that predict seroconversion

Status: Completed
Phase of Trial: Phase IV

Latest Information Update: 13 Jul 2020

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At a glance

  • Drugs Adjuvanted Hepatitis-B vaccine (Recombinant)-Dynavax (Primary) ; Hepatitis B vaccine recombinant
  • Indications Hepatitis B
  • Focus Pharmacodynamics

    • Most Recent Events

    • 13 Jul 2020 Primary endpoint (achievement of immunity at least 2 months after the completion of the hepatitis B vaccine series) has not been met, according to results published in the Digestive Diseases and Sciences
    • 13 Jul 2020 New trial record
    • 02 Jul 2020 Results published in the Digestive Diseases and Sciences

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