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A First-in-Human Study of [18F]EKZ-001 in healthy volunteers

Trial Profile

A First-in-Human Study of [18F]EKZ-001 in healthy volunteers

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 13 Jul 2020

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At a glance

  • Drugs Fluorine-18 Bavarostat (Primary)
  • Indications Alzheimer's disease; Amyotrophic lateral sclerosis
  • Focus Diagnostic use; First in man; Pharmacokinetics
  • Sponsors Eikonizo Therapeutics

Most Recent Events

  • 13 Jul 2020 New trial record
  • 08 Jul 2020 According to an Eikonizo Therapeutics media release, the study was approved by the independent Ethics Committee of the University Hospitals of KU Leuven and was performed in accordance with the World Medical Association Declaration of Helsinki.
  • 08 Jul 2020 According to an Eikonizo Therapeutics media release, the company plans to use [18F]EKZ-001 PET to confirm and quantify brain HDAC6 target engagement by Eikonizo's drug candidates in therapeutic clinical trials.

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