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A Randomized, Placebo-Controlled, Double-Blind Study of XPro1595 in Patients With Early Alzheimer's Disease With Biomarkers of Inflammation

Trial Profile

A Randomized, Placebo-Controlled, Double-Blind Study of XPro1595 in Patients With Early Alzheimer's Disease With Biomarkers of Inflammation

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 06 Apr 2026

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At a glance

  • Drugs Pegipanermin (Primary)
  • Indications Alzheimer's disease
  • Focus Proof of concept; Therapeutic Use
  • Acronyms MINDFuL
  • Sponsors INmune Bio

Most Recent Events

  • 19 Mar 2026 According to an INmune Bio media release, data from this trial presented at AD/PD 2026 taking place March 17-21, 2026 in Copenhagen, Denmark.
  • 23 Feb 2026 According to an INmune Bio media release, the company will will host a webinar focused on the registrational pathway of XPro1595 for the treatment of early Alzheimers disease on February 27, 2026 at 9:30 a.m. ET, including detailed presentation of MINDFuL Trial Results and Path to the FDA End-of-Phase 2 Meeting,Registrational Study Design and FDA Feedback and Path to Phase 3 and Maximizing XPro Potential Through Global Partnership and strategic roadmap.
  • 23 Feb 2026 According to an INmune Bio media release, Post the completion of this trial, along with feedback from the FDA in a recent End-Of-Phase 2 meeting, the Company has received alignment supporting advancement to a registrational study in patients with Alzheimers Disease with biomarkers of Inflammation.

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