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A Phase Ib Study of Multivalent Autophagosome Vaccine, With or Without GITR Agonist, With Sequenced Checkpoint Inhibition (Anti-PD-1) - Immunotherapy Trio in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (HNSCC)

Trial Profile

A Phase Ib Study of Multivalent Autophagosome Vaccine, With or Without GITR Agonist, With Sequenced Checkpoint Inhibition (Anti-PD-1) - Immunotherapy Trio in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (HNSCC)

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 13 Nov 2024

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At a glance

  • Drugs DPV 001 (Primary) ; Ragifilimab (Primary) ; Retifanlimab (Primary) ; Cyclophosphamide
  • Indications Head and neck cancer; Squamous cell cancer
  • Focus Adverse reactions; First in man
  • Acronyms GITRVax

Most Recent Events

  • 07 Nov 2024 According to an UbiVac Media Release, updated results from a Phase 1b study presented at this year's Society for Immunotherapy of Cancer (SITC) Annual Meeting.
  • 07 Nov 2024 Results presented in an UbiVac Media Release
  • 18 Jun 2024 Planned End Date changed from 31 Jul 2024 to 31 Dec 2027.

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