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A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study Comparing the Efficacy, Safety, and Tolerability of Subcutaneous Administration of Fremanezumab Versus Placebo for the Preventive Treatment of Chronic Migraine in Pediatric Patients 6 to 17 Years of Age

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Trial Profile

A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study Comparing the Efficacy, Safety, and Tolerability of Subcutaneous Administration of Fremanezumab Versus Placebo for the Preventive Treatment of Chronic Migraine in Pediatric Patients 6 to 17 Years of Age

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 18 Feb 2026

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At a glance

  • Drugs Fremanezumab (Primary)
  • Indications Headache; Migraine
  • Focus Registrational; Therapeutic Use
  • Acronyms SPACE
  • Sponsors Teva Branded Pharmaceutical Products R&D

Most Recent Events

  • 04 Feb 2026 According to a Teva Pharmaceutical Industries media release, based on results from the phase 3 SPACE trial, Health Canada has approved an expanded indication for PrAJOVY (fremanezumab) for the prevention of episodic migraine in pediatric patients aged 6 to 17 years who weigh at least 45 kg.
  • 24 Dec 2024 Status changed from active, no longer recruiting to completed.
  • 09 Oct 2024 Status changed from recruiting to active, no longer recruiting.

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