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Efficacy of Daratumumab Combined With Bortezomib and Dexamethasone in Patients With Mayo 04 Stage III Light Chain Amyloidosis: a Prospective Phase II Clinical Trial

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Trial Profile

Efficacy of Daratumumab Combined With Bortezomib and Dexamethasone in Patients With Mayo 04 Stage III Light Chain Amyloidosis: a Prospective Phase II Clinical Trial

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 07 May 2024

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At a glance

  • Drugs Bortezomib (Primary) ; Daratumumab (Primary) ; Dexamethasone (Primary)
  • Indications Amyloid light-chain amyloidosis
  • Focus Therapeutic Use
  • Most Recent Events

    • 12 Dec 2023 Results (N=47) assessing the efficacy and safety of low-frequency Daratumumab in patients with AL amyloidosis, were presented at the 65th American Society of Hematology Annual Meeting and Exposition.
    • 13 Dec 2022 Results assessing the efficacy and safety of daratumumab plus bortezomib and dexamethasone in high-risk patients with Mayo 2004 stage 3 AL amyloidosis presented at the 64th American Society of Hematology Annual Meeting and Exposition
    • 09 May 2022 Status changed from recruiting to active, no longer recruiting.

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