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A Phase 2, Open-label, Single-arm Study Evaluating the Efficacy, Safety and Tolerability of Lerapolturev (PVSRIPO) and the Immune Checkpoint Inhibitor Pembrolizumab in the Treatment of Patients With Recurrent Glioblastoma

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A Phase 2, Open-label, Single-arm Study Evaluating the Efficacy, Safety and Tolerability of Lerapolturev (PVSRIPO) and the Immune Checkpoint Inhibitor Pembrolizumab in the Treatment of Patients With Recurrent Glioblastoma

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 04 Oct 2023

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At a glance

  • Drugs Lerapolturev (Primary) ; Pembrolizumab (Primary)
  • Indications Glioblastoma
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms LUMINOS-101
  • Sponsors Istari Oncology

    • Most Recent Events

    • 26 Sep 2023 Planned End Date changed from 1 Mar 2023 to 1 Mar 2024.
    • 26 Sep 2023 Planned primary completion date changed from 1 Mar 2023 to 1 Mar 2024.
    • 03 Nov 2021 Status changed from recruiting to active, no longer recruiting.

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