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Phase II Trial of LP-300 in Combination with Carboplatin and Pemetrexed in Never Smoker Patients with Relapsed Advanced Primary Adenocarcinoma of the Lung After Treatment with Tyrosine Kinase Inhibitors (The HARMONIC Study)

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Trial Profile

Phase II Trial of LP-300 in Combination with Carboplatin and Pemetrexed in Never Smoker Patients with Relapsed Advanced Primary Adenocarcinoma of the Lung After Treatment with Tyrosine Kinase Inhibitors (The HARMONIC Study)

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 20 Jun 2025

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At a glance

  • Drugs Dimesna (Primary) ; Carboplatin; Pemetrexed
  • Indications Adenocarcinoma; Bronchiolo-alveolar adenocarcinoma; Carcinoma; Non-small cell lung cancer
  • Focus Therapeutic Use
  • Acronyms HARMONIC; Harmonica
  • Sponsors Lantern Pharma

Most Recent Events

  • 16 Jun 2025 According to a Lantern Pharma media release, the company expects to continue reporting clinical updates from the HARMONIC trial throughout 2025 as enrollment progresses across multiple sites. The company anticipates providing an additional data update from the randomized expansion phase in the second half of 2025.
  • 16 Jun 2025 Results presented in a Lantern Pharma Media Release.
  • 09 Dec 2024 According to a Lantern Pharma media release, Initial results from the Phase 2 clinical trial from the lead-in patient cohort can be reviewed in an earlier press release issued by Lantern Pharma.

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