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Overcoming Resistance to Immunotherapy Combining Gemcitabine With Atezolizumab in Advanced NSCLC and Mesothelioma Progressing Under Immune-checkpoint Inhibitors or Gemcitabine. A Multicenter, Single-arm, Open Label Phase II Trial With Two Cohorts

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Trial Profile

Overcoming Resistance to Immunotherapy Combining Gemcitabine With Atezolizumab in Advanced NSCLC and Mesothelioma Progressing Under Immune-checkpoint Inhibitors or Gemcitabine. A Multicenter, Single-arm, Open Label Phase II Trial With Two Cohorts

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 15 Jul 2024

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At a glance

  • Drugs Atezolizumab (Primary) ; Gemcitabine (Primary)
  • Indications Malignant-mesothelioma; Non-small cell lung cancer; Squamous cell cancer
  • Focus Therapeutic Use
  • Acronyms ORIGIN
  • Most Recent Events

    • 01 Jul 2024 Status changed from active, no longer recruiting to completed.
    • 16 Jan 2024 Planned End Date changed from 1 Sep 2024 to 1 May 2024.
    • 16 Jan 2024 Planned primary completion date changed from 1 Sep 2024 to 1 May 2024.

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