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Phase II Study on Venetoclax (VEN) Plus Decitabine (DEC) (VEN-DEC) for Elderly (≥60 <75years) Patients With Newly Diagnosed Acute Myeloid Leukemia (AML) Elegible for Allogeneic Stem Cell Transplantation (Allo-SCT)

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Trial Profile

Phase II Study on Venetoclax (VEN) Plus Decitabine (DEC) (VEN-DEC) for Elderly (≥60 <75years) Patients With Newly Diagnosed Acute Myeloid Leukemia (AML) Elegible for Allogeneic Stem Cell Transplantation (Allo-SCT)

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 15 Jan 2024

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At a glance

  • Drugs Decitabine (Primary) ; Venetoclax (Primary)
  • Indications Acute myeloid leukaemia
  • Focus Therapeutic Use
  • Acronyms VEN-DEC GITMO Study
  • Most Recent Events

    • 12 Dec 2023 Results of safety and efficacy data in final report presented at the 65th American Society of Hematology Annual Meeting and Exposition
    • 15 Jun 2023 Primary endpoint (Allo-SCT) has been met, as per results presented at the 28th Congress of the European Haematology Association.
    • 15 Jun 2023 Results (Data cut-off date February 18th, 2023) assessing the safety and efficacy of the chemo-free combination venetoclax plus decitabine as bridge to allo-SCT in elderly (greater than equal to 60 to less than 75 years) acute myeloid leukemia patients, presented at the 28th Congress of the European Haematology Association.

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